All three are low-cost telehealth options for compounded semaglutide and tirzepatide, and all three keep pricing flat as your dose climbs, which is the single biggest cost trap to avoid. The differences come down to entry price, plan structure, and shipping. Here's the honest head-to-head.
💸 Skip ahead: run all three through the free cost calculator →| GobyMeds | OrderlyMeds | Trimi | |
|---|---|---|---|
| Semaglutide from | $99/mo | $83/mo (3-mo plan) | $99/mo |
| Tirzepatide from | $133/mo | $166/mo | $125/mo |
| Dose-flat pricing | Yes | Yes | Yes |
| Plan structure | Single monthly plan | 3-month SimpleStart | Flat every dose |
| Shipping | Included, online | Included | Free overnight |
Cheapest semaglutide: OrderlyMeds at $83/mo, but that's on a 3-month prepay plan, so you commit up front. If you want the lowest month-to-month entry with no quarterly commitment, GobyMeds and Trimi tie at $99/mo.
Cheapest tirzepatide: Trimi at $125/mo, edging out GobyMeds ($133) and OrderlyMeds ($166). If tirzepatide is your molecule, Trimi is the value pick of the three.
Want the absolute lowest semaglutide price and don't mind prepaying 3 months? → OrderlyMeds ($83/mo).
Want low semaglutide with month-to-month flexibility? → GobyMeds or Trimi ($99/mo).
On tirzepatide, or want free overnight shipping + flat pricing? → Trimi ($125/mo tirz, $99 sema).
You can't go far wrong on price with any of the three, the key is that all three are dose-flat, which protects you from the biggest hidden cost. Pick OrderlyMeds for the lowest semaglutide price if you'll prepay, GobyMeds or Trimi for low month-to-month semaglutide, and Trimi for the cheapest tirzepatide. Run your exact doses through the free calculator to see your real yearly number, and compare the full 8-provider table on GLP-1 Cost Guides.
GLP-1 Cost Guides is independent and reader-supported. Some links are affiliate links; we may earn a commission if you enroll through them, at no additional cost to you. This never influences our pricing data or rankings. This article is for informational purposes only and is not medical advice, always consult a licensed clinician before starting any GLP-1 medication. Compounded medications are not FDA-approved the way brand-name drugs are. Prices are starting rates and subject to change; confirm current cost with each provider.